ISSR, INC. HEALTH SURVEY UPDATE 2001
by Tina M. Barber
PART III
In our last update we shared some sample (generic)
trait worksheets, just to give you an idea of what we were working
toward. Since Homecoming, we now have the complete reports prepared by
Dr. Padgett, just for our dogs!! However, since George was only able to
work with the facts that were presented to him (and they certainly paint
a very close picture) I would like to go even deeper into the results,
because I know about things that were NOT presented to him. After all,
our main goal is to get as clear a picture of where we were (our past),
where we are (our present), and where we are going (our future), so take
some time to follow those titles as presented here.
To begin with, during Homecoming Dr. Padgett
presented us with an in-depth seminar that I feel everyone should watch!
It is available on tape thanks to our friends Peter, Virginia and crew,
the Canadian film makers ;-) The entire tape is 6 hours long and
includes a lot more charts and information then I can possibly present
here, but this should give you a small idea of what we have been working
on over the past year! After explaining how these figures are tabulated
(please see part 1 and 2 of our reports) he presented us with our own
chart!!
GENETIC DISEASES AND GUESSTIMATED CARRIER
FREQUENCY
OF THE Shiloh Shepherd™
|
No. |
Age of Onset |
Disease |
Mode of Inheritance |
Disease Frequency 0/100 |
Guestimated Carrier Frequency |
|
1 |
<6 months |
Megaesophagus |
Und. |
0.6 |
14.2 |
|
2 |
< 1 year variable |
S.I. Baterial Overgrowth Syndrome |
Und |
7.9 |
40.3 |
|
3 |
<4 years |
Basenji Enteropathy |
Und |
0.3 |
10.2 |
|
4 |
<9 years |
Canine Sprue |
Und |
0.6 |
14.2 |
|
5 |
<7 years |
Bloat/Torsion |
Und |
3.6 |
30.6 |
|
6 |
<8 years |
Idiopathic Canine Colitis |
Und |
3.1 |
29.5 |
|
7 |
<8 years |
Perianal Fistula |
Und |
0.6 |
14.2 |
|
8 |
<3 years |
Aggressive (temperament) |
Und |
1.4 |
20.8 |
|
9 |
<8 years |
Hypothyroidism (autoimmune thyroiditis) |
R |
0.6 |
14.2 |
|
10 |
<5 years |
Addison's Disease |
Und |
0.3 |
10.2 |
|
11 |
<1 year |
Mitral Valve Disease |
Und |
0.3 |
10.2 |
|
12 |
<1 year |
Pulmonic Stenosis |
Poly |
0.6 |
14.2 |
|
13 |
<1 year |
Subaortic Stenosis |
Poly |
1.4 |
20 |
|
14 |
Birth |
Patent Ductus Arteriosis |
Poly |
0.6 |
14.2 |
|
15 |
Birth |
Selective IgA Deficiency |
Und |
0.3 |
10.2 |
|
16 |
<1 year |
Demodicosis |
Und |
3.3 |
29.6 |
|
17 |
<9 years |
Systemic Lupis Erthematosus |
Und |
0.3 |
10.2 |
|
18 |
<1 year |
Pancreatic Hypoplasis |
R |
6.1 |
36.5 |
|
19 |
Varies |
Acral Mutilation Syndrome |
Und |
0.6 |
14.2 |
|
20 |
<2 years |
Contact Dermatitis |
Und |
0.6 |
14.2 |
|
21 |
<11 months |
GSD Foot Pad Syndrome |
Und |
0.3 |
10.2 |
|
22 |
Birth |
Idiopathic Onychomadesis |
Und |
0.3 |
10.2 |
|
23 |
<2 years |
Pemphigus Vulgaris |
Und |
0.3 |
10.2 |
|
24 |
<1 year |
Sebaceous Adenitis (SA) |
R/Und |
0.3 |
10.2 |
|
25 |
<8 years |
Systemic Lupid Onchodystrophy |
Und |
0.3 |
10.2 |
|
26 |
<6 months |
Umbilical Hernia |
R/Poly |
7 |
38.4 |
|
27 |
>1 year |
Epilepsy |
R/Und |
0.3 |
10.2 |
|
28 |
<12 months |
Glycogen Storage Disease |
R |
0.3 |
10.2 |
|
29 |
<13 months |
Spinal Muscular Atrophy |
Und |
0.3 |
10.2 |
|
30 |
<1 year |
Keratoconjunctivitis Sicca |
Und |
0.6 |
14.2 |
|
31 |
<3 years |
Cataracts |
R |
0.3 |
10.2 |
|
32 |
Varies |
Corneal Dystrophy |
Und |
0.3 |
10.2 |
|
33 |
<3 Months |
Crpytorchidism |
R/Und |
1.1 |
18.6 |
|
34 |
<9 years |
Uroliths (Struvite) |
Und |
0.3 |
10.2 |
|
35 |
Birth |
Cleft Lip/Palate |
Poly/Und |
0.3 |
10.2 |
|
36 |
8 months |
Hypertrophic Osteodystrophy |
Und |
0.6 |
14.2 |
|
37 |
<1 year |
Osteochondritis Dissecans (OCD) |
Und |
0.3 |
10.2 |
|
38 |
<1 year |
OCD (FCP/OCD) |
Poly |
0.3 |
10.2 |
|
39 |
<1 year |
Non-fusion of the Anconeus (UAP) |
Und |
0.3 |
10.2 |
|
40 |
<18 months |
Panosteitis |
Und |
13.8 |
46.6 |
|
41 |
<1 year |
Premature Closure Ulna |
R |
0.3 |
10.2 |
|
42 |
Birth |
Spina Bifida |
Und |
0.3 |
10.2 |
|
43 |
<5 months |
Imperfect Dentition |
R/Und |
3.7 |
30.8 |
|
44 |
<1 year |
Overshot |
R/Und |
0.3 |
10.2 |
|
45 |
<1 year |
Undershot |
Poly |
0.3 |
10.2 |
|
46 |
<2 years |
Hip Dysplasia |
Poly |
11.2 |
44.2 |
|
|
|
|
|
|
803.5 |
During this seminar, he also provided us with copies
of some of the articles he had written for Dog World back in 1994. At
the end of his four- part series he highly praised what he called the
Trail-Blazing Breed Clubs, that were "deeply involved in educating
their members about controlling, preventing or eliminating genetic
disease"! Of course, by next year we hope to be added to that list
;-)
Those of you that know me, should also be aware of
the fact that I don’t like to do things "half way." Although
the above chart has done a great job of documenting our situation as
closely as data permitted, I know we can go above and beyond that!! When
I set up the ISSR data collection system, the only thing I missed was a
line for specific genetic diseases. We did list, randomly, things
like SAS, Elbow dysplasia, Mega Esophagus, etc. but did not list each
and every one of the things that have now been reported. Yes, we are
planning to correct this oversight, by starting a collection data base
on our VIB list, so that we can continue to collect this information via
our Licensed Breeders, as well as working with the TCCP to possibly
adjust our present system to also include this data, by adding another
line of information!! During my "fireside" discussion with Dr.
Padgett I showed him one of our TCCP pedigrees, and to say that he was
impressed would be an understatement! <VBG>
Now, let’s take another look at the chart listed
above. This consists of all 3 groups (A – B – C) compiled together.
That is why I felt it did not show an accurate picture of where we stand
at this moment ;( I will explain below, but I do want you to read the
chart carefully, and understand the MOST important part …(CF) Carrier
Frequency. As per this chart, the statistics show that our dogs (for
example) have a CF of 20.8% and that 1.4 pups (per 100 dogs) could be
born with Subaortic Stenosis! Worse yet, if you combine all of the
various heart defects, like Pulmonic Stenosis, etc. those figures rise
drastically!! Just examine the chart and add up the numbers!
Now, for the good news! Despite club splits,
politics, etc. I have been privately documenting SAS carefully, and have
narrowed the potential carriers down drastically! This is an advantage
that only a "breeder" can have, since they receive
"inside" info that is often not present any other way!
Although a few cases about which I was informed (via the splinters)
cannot be honestly documented, and have certainly NOT been added to the
above reports, nevertheless ... they too tell a story that we can use to
improve what we are doing for the future welfare of this breed! Also,
knowing some "inside" information that has never been made
public, has helped me to trace back the lines responsible for this
problem ... then following the incidence has enabled me to better close
in on the specific carriers! I feel strongly that within the next four
generations, we can completely eliminate SAS (as well as some of the
other diseases listed) from our entire gene pool!
OUR PAST
If you take some time to look at the charts listed below,
you should note that in GROUP "A" (dogs that turned one year
of age between ’91-92-93) we had a very Large percentage of Normals
and only 28% Affected, compared to group B (dogs turning one year in ’94-95-96)
and Group C (dogs turning 1 year in ’97-98-99) that only reported 18%
and 19% Normals, respectively ;(
Another thing that you should also note is that we
had much better ‘co-operation’ in group A (the old timers ;-) than
we did in group B (riddled with splinters) while Group C seems to be
"coming back" home to provide data! This is a good trend,
because I honestly feel that by the time we are ready to release data
from Group D, things will look much better again ;-)


OUR
PRESENT
Now
take a moment to look at the next 3 charts that actually list the
diseases reported! You may notice that it appears as if genetic diseases
are becoming more prevalent since additional diseases are being added to the pie ... but in reality, many of
the dogs that have been producing these problems have already gone
"over" to the splinters and will NOT be effecting our
gene pool any longer!! Nevertheless, if we are not careful, we could be
looking at charts that are MUCH worse than these!! So please take some
time to ponder the individual groups, as you keep in mind that many of
those that should have submitted their information to this study did NOT
do so ;(
OUR FUTURE:
Now
that we have spent nearly 2 years researching and working with these
formulas, we are all confident that we can improve our odds drastically.
The next survey, of dogs turning 1 year between 2000 – 2001 and 2002
will tell us how good of a job we have done. But I would like to give
all of you my prediction, based on several facts, listed below.
A) If you do an honest evaluation of the diseases
listed above, you can note that a large % actually fall into the
"Immune Deficient" category. Even Perianal Fistulas are
considered to be immune related!! We have tried to ‘group"
them slightly, but even this chart is incomplete, because
Demodicosis and EPI should also be listed under possible Immune
problems! Weight loss, vomiting, and Intermittent diarrhea could be
caused by many non genetic factors, but it could also be an
indication of potential EPI! The same goes for the "other"
miscellaneous diseases reported. Some could very well have been
influenced by a weakened immune system due to over inbreeding!! I
have written some articles about Inbreeding Depression, and other
problems associated with too much inbreeding! It would behoove you
to take some time to study them!
B) Now if you take some time to look at the Matador
chart listed below, you can note that we have been very busy adding
"New Blood" to our gene pool in order to offset some of the
above problems!
As of this time Artus has sired a total of 14
litters, and his son Zorro has already produced 10!! Orbit has also
produced a fantastic litter that has just turned one year of age, and
one of his sons has already been bred, with more waiting their turns!!
This influx of FRESH blood will certainly help to clean up the
"pollution" that has been created by previous over
inbreeding practices!

Click on
the chart to view in greater detail.
PLEASE NOTE; None of the pups produced by these NB
studs were old enough to enter the data of the last survey, but they
will certainly be making their mark on GROUP D!!
C) Best of all, we have taken some very big steps
within the ISSR to stop the breeding abuse that has been happening for
too long!! Now that people have such a variety of "fraudulent"
registries to go to, we made it a point to tighten up the ISSR more then
ever before!! The serious breeders, concerned with the future welfare of
these dogs, have joined me on the OSS list to revise the New Licensed
Breeders Agreement!! Please be sure to visit our web site! Even if you
don’t have a computer – ask a friend, or even the library, to print
these pages off for you! Those that have signed the new agreement will
be working very closely with me on the VIB list, those that did not
sign, will no longer be breeding ISSR Shiloh Shepherds™!! Future new
breeders will have to go through an apprentice program, prior to
obtaining their license!
Together .. united in our goals to produce the best
dogs we possibly can, so that we can expand this gene pool and preserve
this breed for generations to come .. WE SHALL SUCCEED!!!
But we also need YOUR help!! If your dog is over one
year of age, and falls into the Group D category, don’t wait .. send
in your survey report now!! If you can’t download a copy, call a
member of the Genetic Task Force, and I am sure they will be happy to
send you one ;-) If we all do our part, we CAN greatly reduce the
incidence of Genetic
Diseases in our dogs!!!
Thanks again to our Genetic Task Force!
Pam DymondWeed
Pat Urso
Lyn Segee
Mynde Bunker
Karen Ursel
|
Genetic Task Force Members: 2006 |
| Pam DymondWeed |
Corinne Filipski |
| Pat Urso |
Lilli Anglin |
| Katy Schuele |
Karen Ursel |
| Jessica Schepler |
Debbie Knatz
(webmaster GTF site) |
One of the original members of the Genetic Task
Force, Mynde Bunker, passed away on Oct. 3, 2002. She will be greatly
missed.
|